Influence of Edoxaban on Coagulability and Thrombin Generation: An in Vitro Study Focusing on Thrombelastography
Status:
Unknown status
Trial end date:
2016-03-01
Target enrollment:
Participant gender:
Summary
The influence of different doses of edoxaban on physical characteristics of the clot and
thrombin generation kinetics in blood samples will be studied by in vitro spiking of blood
samples collected from patients treated for heart failure (with and without
hypercoagulability) and from healthy volunteers (with and without hypercoagulability). This
in vitro experiment will help us to:
(i) detect qualitative anticlotting properties of edoxaban. (ii) quantify the anticlotting
properties of edoxaban.