Influence of Dopaminergic Blockade on Stress Responses, Motivation and Emotional Reactivity in Humans.
Status:
Completed
Trial end date:
2020-07-15
Target enrollment:
Participant gender:
Summary
The study aims to identify whether partial blockade of human dopamine signaling with
antipsychotic drugs affects human stress responses, motivation and emotion. 84 healthy adult
participants are planned to complete the study protocol.
Therefore three experiments are planned:
Experiment 1: Influence of amisulpride on human stress responses. Experiment 2: Influence of
amisulpride on motivated effort. Experiment 3: Influence of amisulpride on emotion.
Phase:
N/A
Details
Lead Sponsor:
Philipps University Marburg Medical Center
Collaborators:
University of Hamburg University of Hamburg-Eppendorf