Influence of Dexmedetomidine on the Evoked Potentials During Spine Surgery

• Status: Completed
• Trial end date: 2010-05-01
• Target enrollment: 0
• Participant gender: All

Summary

The purposes of this study are:

1. To evaluate the safety and efficacy of Dexmedetomidine as an adjunct for anesthesia during spine surgery and

2. To investigate the influence of Dexmedetomidine on the evoked potentials.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Washington
• Collaborators: Hospira, Inc.; Hospira, now a wholly owned subsidiary of Pfizer
• Treatments: Dexmedetomidine

Criteria

Inclusion Criteria:

• Adult spine surgery patients requiring evoked potentials monitoring.

Exclusion Criteria:

• Age younger than 18 and older than 80 years

• Patients with moderate neurological deficit

• ASA grade above 3

• Any chronic psychiatric disorder

• Body mass index (BMI) above 35

• Patients with cortical blindness, cataracts, retinal or optic neuropathy, glaucoma, untreated diabetes, active hepatitis, active coronary artery disease, untreated arrhythmias and patients with renal or hepatic insufficiency