Influence of Cincalcet on Cognitive Functions in Healthy Human Subjects

• Status: Completed
• Trial end date: 2012-08-01
• Target enrollment: 0
• Participant gender: All

Summary

To investigate the effects of the calcimimetic agent cinacalcet on cognitive functions in healthy humans.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Prof. Dominique de Quervain, MD
• Collaborator: Clinical Trial Unit, University Hospital Basel, Switzerland
• Treatments: Cinacalcet; Cinacalcet Hydrochloride

Criteria

Inclusion Criteria:

• healthy

• normotensive

• native or fluent German-speaking

• caucasian (European ancestry)

• BMI between 19 and 27 kg/m2

Exclusion Criteria:

• acute or chronic psychiatric or somatic disorder

• pathological ECG

• Low serum calcium

• known hypersensitivity to the IMP

• pregnancy

• breast-feading

• long-term medication within last 3 months

• smoking more than 3 cigarettes per day

• seizures in participants and first degree relatives

• concurrent participation in another study