Influence of Anesthetics on Clinical Outcome During Cardiac Surgery in Adults

• Status: Completed
• Trial end date: 2022-11-26
• Target enrollment: 0
• Participant gender: All

Summary

Abstract Cardiac surgery in adults is associated with the occurrence of post-operative complications. Even minor complications can increase the cost of their treatment. Given the potentially preventable nature of a number of these postoperative complications, preventive methods should be used to improve outcomes after cardiac surgery. One of them, is the choice of anaesthetic technique.

Objectives: To evaluate the effects of sevoflurane, isoflurane and propofol on blood oxygen transport function and body energy expenditure during cardiac surgery in adults.

Materials and methods. A total of 90 patients were included in the study. All patients were divided into 3 groups: 1- (n=30) included patients who were anesthetized with propofol. The second group (n=30) consisted of patients who underwent sevoflurane inhalation anaesthesia. Group 3 (n=30) was treated with isoflurane. All patients underwent coronary artery bypass grafting under cardiopulmonary bypass.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Astana Medical University
• Treatments: Isoflurane; Propofol; Sevoflurane

Criteria

Inclusion Criteria:

• The age is over 40 years old.

• coronary revascularization or >50% stenosis on coronary angiography

• CHD. Multivessel coronary lesions.

• Participants of both sexes will be included in the study

• Signed informed consent

Exclusion Criteria:

• pregnancy (risk to the baby and the mother)

• allergenic patients (anaphylactic shock).

• vulnerable groups.

• current congestive heart failure;

• current unstable angina pectoris;

• preoperative hemodynamic instability, defined as the use of vasopressors;