Influence of Anesthesia on Mechanical Efficiency of Left Ventricle in Patients Undergoing Open Heart Surgery

• Status: Terminated
• Trial end date: 2012-06-27
• Target enrollment: 0
• Participant gender: All

Summary

The aim of the study is to delineate and compare the changes in coupled mechanical properties of left ventricle and arterial vascular bed caused by two popular anesthetic protocols commonly used in cardiac surgery (intravenous, based on the infusion of propofol, versus inhalational, based on isoflurane) on different stages of the surgery.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Sheba Medical Center
• Treatments: Anesthetics; Isoflurane; Propofol

Criteria

Inclusion Criteria:

• Patients undergoing elective cardiac surgery

Exclusion Criteria:

• Emergent surgery.

• History of previous cardiac surgery.

• Significant arrhythmias.

• More than trivial valvular disorder.

• Absence of written informed consent.

• Contraindications for transesophageal echocardiography.

• Pregnant women.