Inflammatory Responses to Lipid Emulsions in Children Before and After Open Heart Surgery
Status:
Completed
Trial end date:
2007-11-01
Target enrollment:
Participant gender:
Summary
This study is a blinded, randomized, controlled prospective trial comparing immune response
(sepsis, inflammatory response, pulmonary vasoconstriction) in 2 groups of infants less than
3-month old receiving pre and post cardiopulmonary bypass surgery. The infants will receive 1
out of the 2 following intravenous lipid preparations: Soybean Oil (n-6), or a combination of
Medium Chain Triglyceride i.e. coconut oil, Long Chain Triglyceride i.e. Soybean Oil, and
Fish Oil (MCT:LCT:FO). There will be 16 subjects in each group.