Inflammatory Markers and Cognitive Function in Major Depression
Status:
Unknown status
Trial end date:
2013-08-01
Target enrollment:
Participant gender:
Summary
Major depression is accompanied by cognitive changes as well as alterations in multiple
physical functions. The inflammatory system is altered generally toward a pro-inflammatory
state. Antidepressants are associated with a decrease in this proinflammatory state. This
study aims to generate pilot data concerning a possible link between cognition, inflammation
and response to treatment. The cognitive function of subjects with major depression will be
tested before and after treatment with duloxetine. Inflammatory markers will be measured at
both time points.
Phase:
Phase 4
Details
Lead Sponsor:
Centre de Recherche de l'Institut Universitaire en santé Mentale de Montréal Centre de recherche Fernand-Seguin, Hôpital Louis-H. Lafontaine