Induction of Migraine Aura With Sildenafil

• Status: Active, not recruiting
• Trial end date: 2021-03-01
• Target enrollment: 0
• Participant gender: All

Summary

In a double blind placebo-controlled cross-over study the effect of Sildenafil on aura and migraine headache induction is tested in patient with migraine with aura.

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Herlev Hospital
• Treatments: Sildenafil Citrate

Criteria

Inclusion Criteria:

• Migraine with aura

• Minimum of 2 attacks/year

Exclusion Criteria:

• Any other type of headache, except tension-type headache < 4 days per month

• History of cardio- or cerebrovascular diseases

• Hypertension or hypotension

• Any daily intake of medication, including prophylactic migraine treatment, except oral contraceptives

• Pregnancy and lactation