Induction of Anesthesia With Sevoflurane Preserving Spontaneous Breathing: Cardiorespiratory Effects.
Status:
Completed
Trial end date:
2021-07-14
Target enrollment:
Participant gender:
Summary
Airway management is of outmost importance in the perioperative period. One of the main
questions while making a plan for airway management is whether spontaneous ventilation should
be maintained or not. Induction of anesthesia with Sevoflurane is a conventional technique
that preserves spontaneous ventilation. It is used especially in non-collaborating patients
or when other pharmaceutical agents or sophisticated airway management equipment is out of
reach.
Inhalational induction of anesthesia with Sevoflurane is well studied. However, there are few
studies investigating the effects of Sevoflurane on induction and intubating conditions, on
cardiopulmonary physiology, on emergence conditions, when it is used as one and only agent to
achieve induction of anesthesia, intubation and maintenance of anesthesia in adult patients.
There is also no consensus on the appropriate duration of the inhalational induction or other
criteria to guarantee successful intubation conditions, since most studies investigate
Sevoflurane administration until induction of anesthesia and not until intubation.
From all the above, it appears that there are a few gaps in the management of patients who
are to be intubated with Sevoflurane only, without the use of any other anesthetic agents.