Overview

Induction and Maintenance of Remission With Pentasa as Ulcerative Colitis Treatment

Status:
Completed
Trial end date:
2019-01-14
Target enrollment:
0
Participant gender:
All
Summary
For both induction of remission and in maintenance of remission, different doses and treatment durations are used in practice. The aim of this study is to assess how mesalazine is used in clinical practice, at which doses and for how long and how these differences impact the patient disease state and work productivity.
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Ferring Pharmaceuticals
Treatments:
Mesalamine
Criteria
Inclusion Criteria:

- Patients with mild to moderate active ulcerative colitis with disease extension beyond
the rectum (≥ 10 cm) who will receive oral Pentasa treatment (Compact sachets and/or
tablets) for the treatment of the current active episode or in whom on oral Pentasa
maintenance treatment induction of remission treatment will be initiated by dose
escalation. Treatment combined with Pentasa enema (1g/100ml) is allowed.

- Informed consent

Exclusion Criteria:

- Patients receiving treatment with one or more of the following: locally acting
steroids (e.g. budesonide, beclomethasone), systemic steroids, immunosuppressants
(e.g. thiopurines), biologicals (e.g. anti-Tumor Necrosis Factor-alpha)