Overview

Induction Therapy for Patients With FLT3 Mutated Acute Myeloid Leukemia

Status:
Not yet recruiting
Trial end date:
2032-08-01
Target enrollment:
Participant gender:
Summary
This is a pilot study designed to identify the effect of daunorubicin-cytarabine liposome (CPX-351) in combination with a FLT3-inhibitor (midostaurin) as induction and consolidation therapy for patients with high-risk FLT3 mutated acute myeloid leukemia (AML) and subsequent CD34+-selected allogeneic stem cell transplant from HLA compatible related or unrelated donors.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Baptist Health South Florida
Collaborator:
Jazz Pharmaceuticals
Treatments:
Busulfan
Fludarabine
Melphalan
Midostaurin