Indomethacin and Mechanisms Underlying Risk of Falling

• Status: Completed
• Trial end date: 2007-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether indometacin has an effect on reaction time, postural stability, and the avoidance of obstacles.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Sint Maartenskliniek
• Treatments: Indomethacin

Criteria

Inclusion Criteria:

• Age between 50-70 years old

• Not using any non-steroidal anti-inflammatory drugs (NSAIDs) for at least 3 days prior to the test session

Exclusion Criteria:

• Neurological or orthopedic disorders

• Poor comprehension of Dutch language

• Hearing problems

• Severe problems with heart and/or blood vessels

• Acutely existing ulcus ventriculi and/or duodeni, or history of ulcus

• Allergy against indomethacin, aspirin, or other NSAIDs

• Patients with nasal polyps reacting with an angioedema to other NSAIDs

• Severe preexisting renal and liver damage

• Co-medication

• Over 100 kg of weight