Indomethacin Prophylaxis for Heterotopic Ossification After Surgical Treatment of Elbow Trauma

• Status: Unknown status
• Trial end date: 2019-11-01
• Target enrollment: 0
• Participant gender: All

Summary

Patients who present to our institution with a traumatic injury to their elbow who need operative management will be randomized to one of two groups; a treatment arm and a control arm. The treatment arm will receive a three-week postoperative course of indomethacin while the control group will not. We will follow both groups to assess whether or not indomethacin prophylaxis affects the rate of heterotopic ossification.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Lawson Health Research Institute
• Treatments: Indomethacin; Pantoprazole

Criteria

Inclusion Criteria:

• Terrible Triad

• Radial head fracture surgical treatment

• Monteggia and Trans-olecranon Fracture Dislocations

• Distal Biceps Tendon Injuries

• Distal Humerus Fractures

• Coronoid Fractures

• Capitellar-Trochlear fractures

• Olecranon Fractures

Exclusion Criteria:

• Associated Traumatic Brain Injury

• Burn Injuries associated with elbow trauma

• History of Gastric Ulcers

• Documented allergies to any Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)

• Severe Asthma

• Previous operative fixation to affected elbow

• Participation in other research study

• Inability to speak / understand English