Individualized Temozolomide in Treating Patients With Stage IV Melanoma That Cannot Be Removed By Surgery
Status:
Completed
Trial end date:
2018-07-11
Target enrollment:
Participant gender:
Summary
This clinical trial studies individualized temozolomide (TMZ) in treating patients with stage
IV melanoma that cannot be removed by surgery. Drugs used in chemotherapy, such as TMZ, work
in different ways to stop the growth of tumor cells, either by killing the cells or by
stopping them from dividing. Giving TMZ at different times, which are determined individually
for each patient based on the phase (biorhythm) of the immune system response against the
tumor may allow for a better drug response and may kill more tumor cells