Individualized Dosing Schedule of Inhaled Bronchodilator for Endotracheally Intubated COPD Patients

• Status: Completed
• Trial end date: 2019-01-31
• Target enrollment: 0
• Participant gender: All

Summary

This study evaluates whether individualized dosing schedule of inhaled bronchodilator is more effective than fixed dosing in reducing airway resistance of intubated COPD patients.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Shin-hwar Wu
• Treatments: Albuterol; Bronchodilator Agents; Fenoterol; Fluticasone; Fluticasone Propionate, Salmeterol Xinafoate Drug Combination; Methylprednisolone; Methylprednisolone acetate; Methylprednisolone Hemisuccinate; Prednisolone; Prednisolone acetate; Prednisolone hemisuccinate; Prednisolone phosphate; Salmeterol Xinafoate

Criteria

Inclusion Criteria:

• chronic obstructive pulmonary disease

• acute respiratory failure under ventilator support for less than 72 hours

• endotracheal tube inserted

Exclusion Criteria:

• confirmed asthma

• Acute Physiology and Chronic Health Evaluation II score over 35

• a co-morbidity of septic shock