Individual Differences in the Response to Drugs

• Status: Completed
• Trial end date: 2013-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to examine whether individual differences in acute responses to drugs co-vary across three drugs from different drug classes: alcohol, amphetamine and delta-9-tetrahydrocannabinol (THC). The investigators hypothesize that individuals who experience greater rewarding effects from one drug will also experience more rewarding effects from the other drugs.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Chicago
• Treatments: Amphetamine; Dextroamphetamine; Dronabinol; Ethanol

Criteria

Inclusion Criteria:

• English fluency

• High school education

• BMI between 19 and 26

• Individuals who report drinking at least 4 alcoholic drinks on one occasion in the past month

Exclusion Criteria:

• individuals with a medical condition contraindicating study participation, as determined by our physician

• individuals regularly using any contraindicated medications

• individuals with current dependence on any drug or past dependence on alcohol, marijuana or stimulants

• individuals with a past year DSM-IV Axis I mood, anxiety, eating, or psychotic disorder

• women who are pregnant, nursing, or planning to become pregnant in the next 3 months

• individuals who drink more than 10 alcoholic drinks per week

• individuals who currently use i) any illicit drug weekly or more frequently, ii) stimulant prescription drugs, iii) more than 10 cigarettes per week, and iv) more than 3 cups of coffee per day