Incomplete Response in Late-Life Depression: Getting to Remission With Buprenorphine
Status:
Completed
Trial end date:
2018-05-01
Target enrollment:
Participant gender:
Summary
The Investigators are conducting a research study to learn about the safety and benefit of
using a medication called buprenorphine for patient with difficult to treat depression . This
research study is testing whether combining two medications will be effective in treating
depression when initial treatment with just one antidepressant does not relieve the
depressive symptoms ; this is what is called " difficult to treat depression " or " treatment
resistant depression ". The two medication the investigators are using are " an
anti-depressant medication called venlafaxine XR ( the generic form of Effexor ) and
buprenorphine . Buprenorphine is a medication that is FDA approved for the treatment of
opioid dependence. The investigators are testing whether adding buprenorphine to venlafaxine
enhances treatment response.