Overview

In Vivo Assessment of Cellular Metabolism in Humans

Status:
Active, not recruiting
Trial end date:
2022-12-31
Target enrollment:
Participant gender:
Summary
This is a pilot study to establish an arterial venous methodology to measure the activity of the TCA cycle or flux directly in tissues of human beings. It will also perform correlative studies to study the proteome, metabolome, oxygen consumption, carbon dioxide production and exosomes derived from the arterial venous supply of tissues with correlation to the TCA cycle activity.
Phase:
Phase 1
Details
Lead Sponsor:
K. Sreekumaran Nair
Collaborator:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Treatments:
Glucagon
Glucagon-Like Peptide 1
Hormones
Somatostatin