In Utero Repair of Myelomeningocele: Atosiban Versus Terbutaline
Status:
Recruiting
Trial end date:
2021-01-08
Target enrollment:
Participant gender:
Summary
Myelomeningocele is a malformation with high incidence, and it consists in a neural tube
defect. Fetal intrauterine surgery is an alternative for correction, and it improves the
prognosis of the fetus, but has an increased risk of maternal complications and premature
labor, as it can occur due to uterine stimulation. It is therefore essential that tocolysis
is performed before, during and after surgery, and the most commonly used tocolytics are
terbutaline and atosiban. Terbutaline has no specificity and may have several adverse effects
such as maternal acidosis.