Overview

Improving Pre-operative Systemic Therapy for Human Epidermal Growth Factor Receptor 2 (HER2) Amplified Breast Cancer

Status:
Terminated
Trial end date:
2021-06-30
Target enrollment:
Participant gender:
Summary
This is a phase 2 study evaluating medical treatment before surgery in HER2-amplified early breast cancer patients. Patients receive chemotherapy with HER2-targeted antibodies and are randomised to receive the checkpoint inhibitor atezolizumab or not.
Phase:
Phase 2
Details
Lead Sponsor:
Renske Altena
Treatments:
Ado-Trastuzumab Emtansine
Atezolizumab
Carboplatin
Cyclophosphamide
Docetaxel
Epirubicin
Maytansine
Mitogens
Pertuzumab
Trastuzumab