Improving Dosing of Vancomycin in Young Infants With Infections
Status:
Completed
Trial end date:
2021-01-03
Target enrollment:
Participant gender:
Summary
Current dosing regimens for vancomycin result in many young infants not reaching the target
level of vancomycin in the blood at steady state (when the blood is in equilibrium at 24-48
hours).The purpose of this study is to assess an improved method of calculating the dose of
vancomycin ('model-based dosing') in young infants with infections in order for them to
achieve the target vancomycin level at steady state. A dosing calculator (which will be
available through a web application) will be used for the dose calculation.
Phase:
Phase 4
Details
Lead Sponsor:
Murdoch Childrens Research Institute
Collaborators:
Monash Health Royal Children's Hospital Royal Hospital For Women Sydney Children's Hospitals Network University of Otago