Overview

Importance of the GH/IGF-1 Axis for Human Substrate and Energy Metabolism During Calorie Restriction

Status:
Completed
Trial end date:
2011-09-01
Target enrollment:
0
Participant gender:
Male
Summary
This study will investigate whether growth hormone is modulated by the enzyme SIRT1 and by that is stimulating lipolysis on expense of IGF-I production. This is done in 10 healthy men on calorie restriction on 4 study days with fat and skeletal muscle biopsies.
Phase:
N/A
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
University of Aarhus
Treatments:
Hormones
Criteria
Inclusion Criteria:

- healthy lean men

- age >18

Exclusion Criteria:

- metabolic disturbances

- alcohol drug abuse

- malign disease: current or previous