Importance of the GH/IGF-1 Axis for Human Substrate and Energy Metabolism During Calorie Restriction
Status:
Completed
Trial end date:
2011-09-01
Target enrollment:
Participant gender:
Summary
This study will investigate whether growth hormone is modulated by the enzyme SIRT1 and by
that is stimulating lipolysis on expense of IGF-I production. This is done in 10 healthy men
on calorie restriction on 4 study days with fat and skeletal muscle biopsies.