Implications and Stability of Clinical and Molecular Phenotypes of Severe Asthma
Status:
Active, not recruiting
Trial end date:
2022-03-01
Target enrollment:
Participant gender:
Summary
The Severe Asthma Research Program III is an NIH cooperative agreement involving 7 clinical
centers that encompass a multidisciplinary partnerships between asthma clinician-scientists
and scientists with expertise in immunology, pulmonary physiology, molecular genetics,
molecular phenotyping, imaging, and bioinformatics. These clinical centers will jointly
recruit volunteers with asthma for an observational longitudinal follow-up study. However,
centers will also conduct specific mechanistic research projects at each participating
institution. The University of Pittsburgh's SARP III study will determine the molecular and
clinical stability of asthma phenotypes over time.