Impact of iv Dexamethasone on Reversal of Rocuronium-induced Neuromuscular Block by Sugammadex
Status:
Withdrawn
Trial end date:
2018-05-01
Target enrollment:
Participant gender:
Summary
Sugammadex is used as a reversal drug for rocuronium- or vecuronium-induced neuromuscular
block during general anaesthesia. IV dexamethasone is injected as a prophylactic measure
against postoperative nausea and vomiting. Recent animal data have shown that dexamethasone
may impair the reversal effect of sugammadex. The objective of this randomised controlled
trial is to confirm in the clinical practice these preliminary results.