Impact of Uterotonic Agents on Isolated Human Myometrium
Status:
Completed
Trial end date:
2013-08-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to compare the ability of a sample of uterine muscle tissue to
contract in the presence of various drugs. The drugs studied are typically used to contract
the uterus when a pregnant patient continues to bleed after delivery. Amongst the uterotonic
drugs (used to contract the uterus), namely oxytocin, ergonovine and carboprost, the most
effective one to use is not known.
The investigators will be testing uterine muscle samples in the presence of these drugs at
various concentrations, to see what their contractility measures over time, as compared with
a control sample, in which no drugs will be applied.
Phase:
N/A
Details
Lead Sponsor:
Samuel Lunenfeld Research Institute, Mount Sinai Hospital