Impact of Timing on the Efficacy of Zegerid 40 mg in Healing Reflux Esophagitis: A Pilot Study
Status:
Completed
Trial end date:
2010-12-01
Target enrollment:
Participant gender:
Summary
The purpose of this study was to determine the effect of morning versus bedtime
administration of omeprazole/sodium bicarbonate (Zegerid) on endoscopic healing for patients
with moderate or severe reflux esophagitis. Our hypothesis was that bedtime administration of
Zegerid would be superior in healing esophagitis compared to morning administration prior to
a meal.
Phase:
Phase 4
Details
Lead Sponsor:
Yvonne Romero
Collaborators:
Bausch Health Americas, Inc. Valeant Pharmaceuticals International, Inc.
Treatments:
Omeprazole Omeprazole, sodium bicarbonate drug combination