Impact of Probiotic Regimen on Vancomycin Resistant Enterococcus Intestinal Carriage

• Status: Unknown status
• Trial end date: 2009-08-01
• Target enrollment: 0
• Participant gender: All

Summary

This study aims to reduce the duration of VRE intestinal carriage by the administration of Lactobacillus casei rhamnosus (strain Lcr 35 LC). Patients will be blindly randomized to be assigned to a 5 weeks regimen with the probiotic (10 9 lactobacillus bid) or to a 5 weeks regimen with placebo.A stool culture will be performed every week for 5 weeks (during the administration of treatment) then every two weeks until 3 consecutive negative stool culture for VRE.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Hospital, Clermont-Ferrand
• Treatments: Vancomycin

Criteria

Inclusion Criteria:

• Age >18;

• Vancomycin Resistant Enterococcus intestinal carriage

Exclusion Criteria:

• Neutropenia <1000 /mm3,

• Immunosuppressive drugs,

• Inhalation