Impact of N-acetylcysteine Infusion and Intralipid Infusion on Myocardial Injury in Aluminum Phosphide Toxicity

• Status: Not yet recruiting
• Trial end date: 2025-05-01
• Target enrollment: 0
• Participant gender: All

Summary

Assess impact of ILE and NAC in morbidity and mortality when used as adjuvant therapy to routine management of acute ALP poisoning.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Assiut University
• Treatments: Acetylcysteine; N-monoacetylcystine

Criteria

Inclusion Criteria:

• Presentation with symptomatic acute ALP poisoning.

• History of exposure including reliable identification of the compound based on the container brought by patient's relatives.

• The suggestive clinical manifestations following shortly after a single exposure to ALP.

Exclusion Criteria:

• Co-ingestion or exposure to other substances in addition to ALP.

• Patients had major medical conditions (e.g., cardiovascular disease, renal or hepatic failure).

• Patients received treatment in any hospital or medical center before admission - other than emergency department of Assiut University Hospital.