Impact of Lipoic Acid Use on Stroke Outcome After Reperfusion Therapy in Patients With Diabetes (IMPORTANT)

• Status: Recruiting
• Trial end date: 2021-12-31
• Target enrollment: 0
• Participant gender: All

Summary

This study aims to investigate the effectiveness and safety of alpha-lipoic acid in patients with diabetes and ischemic stroke treated with reperfusion therapy.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Chonnam National University Hospital
• Collaborators: Chonbuk National University Hospital; Chosun University Hospital; Wonkwang University Hospital
• Treatments: Thioctic Acid

Criteria

Inclusion Criteria:

• Patients with acute ischemic stroke within 6 hours of symptom onset

• Patients with diabetes

• Patients who underwent reperfusion therapy (Intravenous t-PA or endovascular thrombectomy)

Exclusion Criteria:

• Pre-existing disability (Modified Rankin Scale >= 1)

• Patients with severe renal disease (GFR <30 ml / min)

• Patients whose survival period is expected to be less than 12 months due to serious diseases such as terminal cancer or liver failure