Impact of Lidocaine Administration on Postoperative Complications During Lung Resection Surgery
Status:
Completed
Trial end date:
2021-07-02
Target enrollment:
Participant gender:
Summary
The purpose of this study is to analyze the impact of the intravenous (IV) or paravertebral
(PV) lidocaine administration during the intraoperative period of lung resection surgery on
the appearance of postoperative complications. We design a randomized, controlled and blinded
study to be performed in 153 patients with 3 arms: 1) Lidocaine IV + PV saline 2) saline IV +
PV lidocaine, 3) remifentanil IV + PV saline. Perioperative analysis of inflammatory
biomarkers in bronchoalveolar lavage and serum. Follow-up of the postoperative course,
especially the appearance of postoperative complications according to the revised
Clavien-Dindo classification for thoracic surgery, as well as other relevant clinical
results.