Impact of Intrathecal vs Intravenous Dexmedetomidine
Status:
NOT_YET_RECRUITING
Trial end date:
2024-12-31
Target enrollment:
Participant gender:
Summary
The purpose of this research is to evaluate the impact of intrathecal dexmedetomidine in comparison with intravenous route in patients undergoing cesarean section.
Alternate hypothesis :Dexmedetomidine is more effective when given intrathecally as adjuvant to bupivacaine in elective cesarean section Null Hypothesis: Dexmedetomidine is more effective when given intravenously as adjuvant to bupivacaine in elective cesarean section Study Design: Randomized controlled trial Study setting: Watim General Hospital Study Duration: 18 months after synopsis approval Sampling technique: Simple random sampling Sample Size: Using the Open Epi program, a sample size of 60 patients (30 in each group) was determined with a 95% confidence interval and 80% power.
Inclusion Criteria:
* Pregnant women between ages 18-35 years
* Belongs to ASA class I or II
* Subjected to elective C-section
Exclusion Criteria:
* Any history of gastrointestinal disease diabetes, thyroid disease, hypertension, obesity, or anemia
* History of alcohol or drug abuse;
* Major complications of pregnancy
* Patients have contraindication to spinal block or allergic to any of drug