Impact of Interferon Free Regimens in Patients With Chronic HCV and Successfully Treated HCC

• Status: Unknown status
• Trial end date: 2019-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The study will recruit 150 patients with HCV related HCC ,after HCC treatment the patients will undergo treatment with different regimens of DAAs.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: National Hepatology & Tropical Medicine Research Institute
• Collaborator: Cairo University
• Treatments: Interferons; Ledipasvir; Ribavirin; Simeprevir; Sofosbuvir

Criteria

Inclusion Criteria:

• Age 18-70 years old

• Confirmed HCV viremia by PCR

• CHILD Pugh "A" or "B7,B8"

• Confirmed HCC either by laboratory ,imaging or histopathological criteria

• Underwent or candidate for curative intervention for HCC (BCLC stage 0 ,A)

• Willing to be treated for HCV and signing informed consent

Exclusion Criteria:

• Patients below 18 or above 70 years old

• patients with advanced liver condition "CHILD score ≥ B9"

• Patients with advanced HCC status (BCLC≥ B)

• Patients with combined HBV ,HIV infection