Impact of Imipenem With Amikacin Pharmacokinetic and Pharmacodynamic
Status:
Completed
Trial end date:
2012-01-01
Target enrollment:
Participant gender:
Summary
The study is a prospective open trial conducted in 4 centers, and designed to determine if
pharmacokinetic (PK) and pharmacodynamic (PD) parameters of imipenem, associated with
amikacin as empirical therapy, impact microbiological and clinical outcome of patients with
Gram negative bacilli (GNB) ventilator-associated pneumonia (VAP).