Impact of Hypertonic Saline Solution on Acute Decompensated Heart Failure
Status:
Recruiting
Trial end date:
2023-09-01
Target enrollment:
Participant gender:
Summary
Acute decompensated heart failure (HF) is one of the most common cardiologic issues in
emergency departments.
Loop diuretics have long been recognized as the key for the treatment of Acute Decompensated
Heart Failure (ADHF).However, chronic treatment with diuretics may limit their response and
deteriorates the renal function. The hypertonic saline solution (HSS) has been proposed in
recent years as an adjunctive therapy for intravenous loop diuretics to improve or restore
their initial pharmacological efficacy.
In this study the investigators will evaluate the effectiveness of HSS as an adjunct to i.v.
furosemide in patients admitted for AHF with renal dysfunction