Impact of Hydrocortisone Administration on White Blood Cell Gene Expression in Patients With Severe Sepsis
Status:
Completed
Trial end date:
2006-11-01
Target enrollment:
Participant gender:
Summary
The purpose of this pilot study is to (1) examine the changes in gene expression in patients
who suffer from severe sepsis and whose shock (inadequate oxygen delivery to vital organs)
state does not respond to fluid and vasopressor administration, (2) to show that our sampling
method of isolating RNA provides reliable and consistent data, (3) provide a basis for future
gene expression studies in critically ill patients
Details
Lead Sponsor:
Stanford University
Collaborators:
University of Colorado, Denver University of Toronto