Overview

Impact of Hot Flashes on Sleep and Mood Disturbance

Status:
Completed
Trial end date:
2012-01-04
Target enrollment:
Participant gender:
Summary
We plan to enroll premenopausal women in a trial investigating the impact of hot flashes developed in response to an injection of a gonadotropin-releasing hormone agonist (GnRHa), leuprolide (brand name: Lupron), on sleep disruption and mood. This study is designed to mimic the menopause transition. We will collect data on sleep disruption and mood changes to assess their relationship to the development of hot flashes.
Phase:
Phase 4
Details
Lead Sponsor:
Hadine Joffe, MD
Massachusetts General Hospital
Collaborator:
National Institute of Mental Health (NIMH)
Treatments:
Deslorelin
Leuprolide