Impact of Heparin on the Need for Mechanical Ventilation in Neonates

• Status: Unknown status
• Trial end date: 2007-03-01
• Target enrollment: 0
• Participant gender: All

Summary

This study is designed to test an incidental finding of a previous trial in which post hoc analysis showed that the rate of intensive care newborns requiring mechanical ventilation was lower in the group receiving heparin with the continuous infusion as compared to the placebo group.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Medicine Greifswald
• Treatments: Calcium heparin; Heparin

Criteria

Inclusion Criteria:

• Newborns < day 28 of life

• Necessity for intensive care treatment

• Necessity for parenteral drug or fluid application for at least five days

• Informed consent of parents

Exclusion Criteria:

• Body weight < 500g

• Mechanical ventilation directly after birth

• Major malformations

• Absolute indication for heparin

• Inborn hemorrhagic disease (e.g. hemophilia, von Willebrand disease)

• Cerebral bleeding or other major bleeding

• Platelet count < 50,000/µl