Impact of Folates in the Care of the Male Infertility
Status:
Completed
Trial end date:
2016-04-01
Target enrollment:
Participant gender:
Summary
Unexplained male infertility is increasing, and, nowadays, the investigators only can propose
palliative treatment, as In VITRO Fertilization (IVF). The folate metabolism is a key for the
maintenance of genome integrity. A dysfunction in this pathway can be responsible of
spermatogenesis defects, and further, of infertility. Few assays have shown that folate
treatment can improve sperm parameters and fertility, till 30% in some of theses studies. The
purpose of the investigators study is to demonstrate the impact of folates treatment on
improvement of sperm parameters and on the rate of success of in VITRO fertilization
procedures.