Overview

Impact of Estradiol on Endothelial Function in Peri-Menopausal Women

Status:
Recruiting
Trial end date:
2025-06-30
Target enrollment:
Participant gender:
Summary
The purpose of this study is to identify the impact of estradiol (E2) on the mechanisms that regulate vascular endothelial function in peri-menopausal (PERI) women. This study is the first step in understanding factors contributing to endothelial dysfunction in women with advancing reproductive age and in response to E2 administration.
Phase:
Phase 4
Details
Lead Sponsor:
University of Delaware
Collaborator:
National Heart, Lung, and Blood Institute (NHLBI)
Treatments:
Estradiol
Estradiol 17 beta-cypionate
Estradiol 3-benzoate
Polyestradiol phosphate