Overview

Impact of Epidural Morphine on Shoulder Pain Following Thoracotomy.

Status:
Terminated
Trial end date:
2014-05-01
Target enrollment:
0
Participant gender:
All
Summary
This study is designed to assess the impact of epidural morphine on: - The incidence and severity of shoulder pain following a thoracotomy. - The need for additional analgesics, such as opioids for the relief of shoulder pain. - Its safety profile compared to epidural fentanyl following a thoracotomy. The basic hypothesis of this study is that an infusion of epidural bupivacaine and morphine initiated after the induction of anesthesia and continued until 72 hours postoperatively will reduce the incidence and severity of shoulder pain following a thoracotomy when compared to an epidural infusion of bupivacaine and fentanyl.
Phase:
N/A
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Centre hospitalier de l'Université de Montréal (CHUM)
Treatments:
Bupivacaine
Fentanyl
Morphine
Criteria
Inclusion Criteria:

- Patients aged 18 to 75 years

- Scheduled for an elective thoracotomy

- Physical status 1-3

Exclusion Criteria:

- Contraindication to epidural analgesia (coagulopathy, sepsis or local infection at the
site of injection, spinal deformity, previous major spinal thoracic surgery)

- A known allergy to local anesthetics, acetaminophen, fentanyl or morphine.

- Pre-existing shoulder pain ipsilateral to the surgery

- Pre-existing chronic pain

- Current use of opioids

- Recent history of alcohol or drug abuse.

- The inability to understand a verbal numerical pain scale (VNPS) despite previous
instruction

- Severe renal insufficiency

- Patient refusal