Overview

Impact of Bromocriptine on Clinical Outcomes for Peripartum Cardiomyopathy

Status:
Not yet recruiting
Trial end date:
2027-01-30
Target enrollment:
Participant gender:
Summary
The study will enroll 200 women newly diagnosed with peripartum cardiomyopathy within 5 months postpartum in a randomized placebo controlled trial of bromocriptine therapy to evaluate its impact on myocardial recovery and clinical outcomes. Given that bromocriptine prevents breastfeeding, an additional 50 women with peripartum cardiomyopathy excluded from the trial due to a desire to continue breastfeeding but meeting all other entry criteria will be followed in an observational cohort.
Phase:
Phase 4
Details
Lead Sponsor:
Dennis McNamara
Collaborator:
National Heart, Lung, and Blood Institute (NHLBI)
Treatments:
Bromocriptine
Rivaroxaban