Overview

Impact of Anesthesia Maintenance Methods on Long-term Survival

Status:
Completed
Trial end date:
2020-09-30
Target enrollment:
Participant gender:
Summary
Surgery is one of the major treatment methods for patients with malignant tumor. And, alone with the ageing process, more and more elderly patients undergo surgery for malignant tumor. Evidence emerges that choice of anesthetics, i.e., either inhalational or intravenous anesthetics, may influence the outcome of elderly patients undergoing cancer surgery. From the point of view of immune function after surgery and invasiveness of malignant tumor cells, propofol intravenous anesthesia may be superior to inhalational anesthesia. However, the clinical significance of these effects remains unclear. Retrospective studies indicated that use of propofol intravenous anesthesia was associated higher long-term survival rate. Prospective studies exploring the effect of anesthetic choice on long-term survival in cancer surgery patients are urgently needed.
Phase:
N/A
Details
Lead Sponsor:
Peking University First Hospital
Collaborators:
Affiliated Hospital of Qinghai University
Beijing Cancer Hospital
Beijing Shijitan Hospital, Capital Medical University
Cancer Hospital of Guangxi Medical University
Guizhou Provincial People's Hospital
Hebei Medical University Fourth Hospital
Peking University Hospital of Stomatology
Shaanxi Provincial People's Hospital
Shanxi Province Cancer Hospital
Shenzhen Second People's Hospital
Tang-Du Hospital
The First Affiliated Hospital of Zhengzhou University
The People's Hospital of Ningxia
The Third Xiangya Hospital of Central South University
Tianjin Nankai Hospital
Zhongda Hospital
Treatments:
Anesthetics
Benzocaine
Nitrous Oxide
Propofol
Sevoflurane