Overview

Immunotherapy in Patients With Metastatic Cancers and CDK12 Mutations

Status:
Recruiting
Trial end date:
2021-09-01
Target enrollment:
Participant gender:
Summary
This study will attempt to determine the efficacy of checkpoint inhibitor immunotherapy with nivolumab and ipilimumab combination therapy followed by nivolumab monotherapy in patients with metastatic prostate cancer harboring loss of CDK12 function.
Phase:
Phase 2
Details
Lead Sponsor:
University of Michigan Cancer Center
University of Michigan Rogel Cancer Center
Collaborators:
Memorial Sloan Kettering Cancer Center
University of California, San Francisco
Treatments:
Ipilimumab
Nivolumab