Immunosuppressant Regimens for Living Fetuses Study
Status:
Recruiting
Trial end date:
2023-02-01
Target enrollment:
Participant gender:
Summary
Undifferentiated connective tissue diseases (UCTD) are known to increase the risk of
pregnancy morbidities, including recurrent pregnancy loss. However, there is no consensus or
guideline about the treatment for recurrent pregnancy loss in UCTD patients. Therefore, based
on the tendency to thrombosis formation and placental inflammation in the pathogenesis of
UCTD, this trial proposes to evaluate the effect of hydroxychloroquine with or without
prednisone combined with anticoagulation on pregnancy outcomes in recurrent pregnancy loss
patients with UCTD.
Phase:
N/A
Details
Lead Sponsor:
RenJi Hospital
Collaborators:
China-Japan Union Hospital, Jilin University The First Affiliated Hospital of Anhui Medical University The First Affiliated Hospital with Nanjing Medical University Wuxi No. 2 People's Hospital Xiangya Hospital of Central South University