Immunologic Responses to a Live Attenuated Oral Cholera Vaccine
Status:
Suspended
Trial end date:
2023-06-30
Target enrollment:
Participant gender:
Summary
The primary objective of this study is to evaluate the antibody response to the cholera
vaccine, Vaxchora®, in healthy subjects.
Investigators also seek to evaluate additional markers of the adaptive immune response
including plasmablasts, activated B cells, memory B cells, and T cell responses in healthy
subjects receiving cholera vaccine, produce monoclonal antibodies against cholera, and
evaluate the safety and reactogenicity in healthy subjects receiving cholera vaccine.