Immunogenicity Study of Vacc-4x Versus Placebo in Patients Infected With HIV
Status:
Completed
Trial end date:
2011-06-01
Target enrollment:
Participant gender:
Summary
Current management of HIV infection includes anti-retroviral therapy (ART). ART cannot cure
the infection, making it a life-long treatment that requires sustained patient compliance and
imposes significant individual and societal financial burdens on healthcare services.
Furthermore, ART side effects often require medication that increases the inconveniences and
financial burdens of HIV management. Of further concern is the emergence of viruses resistant
to ART that can result in treatment failure.
ART-free periods could provide substantial benefit. Vacc-4x is a peptide-based HIV
immunotherapy that is proposed for prolongation of ART-free periods. The purpose of this
study is to determine whether Vacc-4x immunotherapy can give safe ART-free period.