Overview

Immune Disorder HSCT Protocol

Status:
Recruiting
Trial end date:
2024-03-01
Target enrollment:
Participant gender:
Summary
This study hypothesizes that a reduced intensity immunosuppressive preparative regimen will establish engraftment of donor hematopoietic cells with acceptable early and delayed toxicity in patients with immune function disorders. A regimen that maximizes host immune suppression is expected to reduce graft rejection and optimize donor cell engraftment.
Phase:
Phase 2
Details
Lead Sponsor:
Washington University School of Medicine
Treatments:
Alemtuzumab
Fludarabine
Fludarabine phosphate
Melphalan
Thiotepa