Immediate Curative vs Conservative Treatment in Older Men With M0, High-risk Prostate Cancer
Status:
Not yet recruiting
Trial end date:
2036-12-31
Target enrollment:
Participant gender:
Summary
It is currently unclear if immediate curative treatment (radiotherapy or surgery) of
high-risk prostate cancer without metastasis in older men (>=75 years) generates the same
survival benefits as in younger patients or if the harms/ side-effects of immediate curative
treatment outweigh the benefits. In this study we randomize older patients with high-risk,
non-metastatic high-risk prostate cancer to either immediate curative therapy or to
conservative, more problem-oriented therapy to investigate if immediate curative treatment
prolongs life, improves quality of life and is cost-effective.