Overview

Imaging the Effect of Centrotemporal Spikes and Seizures on Language in Children

Status:
Completed
Trial end date:
2017-07-01
Target enrollment:
Participant gender:
Summary
This project examines how seizures, and abnormal brain activity, affect language skill in children with Benign Childhood Epilepsy with Centro-Temporal Spikes (BECTS). BECTS is a common type of childhood epilepsy, and while BECTS patients stop having seizures by their late teenage years, many studies have shown that these children have language problems that may lead to academic and social difficulties. Using standardized language testing, monitoring of brain activity, and MRI brain imaging, this project aims to determine what particular combination of BECTS symptoms put children most at risk for language problems and whether treatment with anti-epileptic medications may be helpful.
Phase:
Phase 1
Details
Lead Sponsor:
Children's Hospital Medical Center, Cincinnati
Collaborator:
National Institute of Neurological Disorders and Stroke (NINDS)
Treatments:
Etiracetam
Levetiracetam
Piracetam